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Dear Sir,

Greeting from Shanghai Chemira Medpharma Co.,Ltd.

I know that you are working the Pregabalin API.

Now we are working on (3S)-3-Cyano-5-methyl-Hexanoic acid ethyl ester ( CAS 181289-39-4) to produce Pregabalin, which is much more cost effective in the market. 

The price for (3S)-3-Cyano-5-methyl-Hexanoic acid ethyl ester ( CAS 181289-39-4) is around USD25/KG CIF SEA NS for 1mt. 

This KSM is different from the traditional manufacturing process to produce Pregabalin intermediate 33-8 to further produce the API.

I hope you can do a check whether you are interested in this new intermediate to improve your competitiveness of Pregabalin API.

Best regards 

Bruce Wu